Ethanimidic acid, 2,2,2-trichloro-, phenylmethyl ester

Ethanimidic acid, 2,2,2-trichloro-, phenylmethyl ester - Names and Identifiers

Name	Benzyl 2,2,2-trichloroacetimidate
Synonyms	BENZYLPHOSPONIC ACID Benzyl trichloroacetimidate Benzyl 2,2,2-trichloroacetimidate Benzyl 2,2,2-trichloroethanimidoate benzyl 2,2,2-trichloroethanimidoate TRICHLOROACETIMIDIC ACID BENZYL ESTER benzyl (1Z)-2,2,2-trichloroethanimidoate 2,2,2-Trichloroacetimidic acid benzyl ester 2,2,2-TRICHLOROACETIMIDIC ACID BENZYL ESTER Ethanimidic acid, 2,2,2-trichloro-, phenylmethyl ester
CAS	81927-55-1
InChI	InChI=1/C9H8Cl3NO/c10-9(11,12)8(13)14-6-7-4-2-1-3-5-7/h1-5,13H,6H2

Ethanimidic acid, 2,2,2-trichloro-, phenylmethyl ester - Physico-chemical Properties

Molecular Formula	C9H8Cl3NO
Molar Mass	252.52
Density	1.359g/mLat 25°C(lit.)
Melting Point	3 °C
Boling Point	106-114°C0.5mm Hg(lit.)
Flash Point	>230°F
Solubility	Miscible with cyclohexane/dichloromethane.
Vapor Presure	0.001mmHg at 25°C
Appearance	Liquid
Color	Clear colorless to yellow
BRN	2525375
pKa	2.23±0.70(Predicted)
Storage Condition	2-8°C
Stability	Moisture Sensitive
Sensitive	Moisture Sensitive
Refractive Index	n20/D 1.545(lit.)
MDL	MFCD00000805
Use	This product is for scientific research only and shall not be used for other purposes.

Ethanimidic acid, 2,2,2-trichloro-, phenylmethyl ester - Risk and Safety

Hazard Symbols	Xn - Harmful
Risk Codes	R22 - Harmful if swallowed R36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
WGK Germany	3
FLUKA BRAND F CODES	8-10-21
HS Code	29252900

Ethanimidic acid, 2,2,2-trichloro-, phenylmethyl ester - Introduction

Benzyl 2,2,2-trichloroacetimidate is a compound with the formula C10H10Cl3NO2. The following is a description of its nature, use, formulation and safety information:

Nature:
- Benzyl 2,2,2-trichloroacetimidate is a colorless liquid or solid.
-It has a spicy smell.
-Its density is about 1.4 g/mL.
-It is soluble in organic solvents such as ethanol and dimethylformamide, but insoluble in water.

Use:
- Benzyl 2,2,2-trichloroacetimidate is mainly used as a protecting group in organic synthesis.
-It can be used to synthesize amino acids and peptide compounds, by protecting hydroxyl or amino functional groups to prevent them from unnecessary side reactions in the reaction.

Preparation Method:
- Benzyl 2,2,2-trichloroacetimidate is usually prepared by reacting trichloroacetate with benzylamine.
-This reaction is usually carried out under alkaline conditions, such as copper carbonate or silver carbonate as a base catalyst.

Safety Information:
- Benzyl 2,2,2-trichloroacetimidate should be operated in a well-ventilated area to avoid inhalation of vapors.
-Wear protective gloves and goggles when using.
-Avoid contact with skin and eyes when handling this compound.
-This compound should be kept away from fire and high temperature objects.
-When storing, it should be sealed and placed in a cool and dry place, away from flammable materials and oxidants.

Please note that for the operation and use of chemicals, it is recommended to strictly follow the safety procedures and use them correctly and safely according to its safety data sheet (SDS).

Last Update：2024-04-10 22:29:15